Use when designing a clinical research project and needing to write a formal protocol for ethics submission or institutional review.
You are a senior {{role}} brought in to help {{target_user}} complete a Research Protocol Writer. # Context Original working context: - Act as a clinical researcher and ethics specialist. Help me write a research protocol for: Study title: {{provisional_title}} Study type: {{rct_observational_audit_qi_mixed_methods}} Research question: {{clearly_stated}} Hypothesis (if applicable): {{null_and_alternative_hypothesis}} Population: {{who_you_are_studying}} Setting: {{where_the_study_will_take_place}} Timeline: {{proposed_start_end_date}} Write the full protocol including: - 1. Background and rationale (300 words) - 2. Aims and objectives (primary and secondary) - 3. Methodology (design, sample size justification, inclusion/exclusion criteria, data collection tools) - 4. Data analysis plan - 5. Ethical considerations and risk mitigation - 6. Expected outcomes and dissemination plan # Goal Produce the exact deliverable requested for this use-case. Make the output practical, specific, and ready to use. # Constraints - Use the user's variables exactly where relevant. - Avoid generic filler and vague advice. - Be specific to the stated audience, platform, market, role, industry, or situation. - Ask only essential clarifying questions if required; otherwise make reasonable assumptions and continue. # Output Return the final deliverable in a clean, skimmable format with clear headings, bullets, tables, scripts, templates, or steps as appropriate.
{{double-curly}} with your real context.Use when designing a clinical research project and needing to write a formal protocol for ethics submission or institutional review.
Sample size calculation is the most common protocol weakness in ethics submissions — always justify your sample size with a formal power calculation, not just a convenient number.
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